A portable urine collection device having a closed loop system that is easily usable by a patient. The urine collection device includes a urine collection receptacle for receiving a fluid from a patient. The urine collection receptacle may be coupled to a reservoir with a conduit. The reservoir may be a disposable plastic bag having markings for determining the amount of urine contained in the bag. The urine collection receptacle may have multiple configurations and may be configured to receive urine from a female or male human being, or both. The urine collection device may also include a pump for pumping urine from the urine collection receptacle to the reservoir without components of the pump contacting the urine being pumped.