A door bolt adjustment system for an open-jamb safe having a door jamb and a door bolt configured to extend behind the door jamb with a gap therebetween. The door bolt adjustment system generally comprises a substantially rigid door bolt adjuster, configured to be attached to the inside of the door jamb, and a displacement mechanism, configured to allow adjustment of the position of the door bolt adjuster so as to occupy the gap. The door bolt adjuster includes a flange for contacting a side of the extended safe door bolt, and when the adjuster occupies the gap, the flange is placed in position for secure contact with the extended door bolt, so as to accommodate the alignment of the door bolt.