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US Patent 6841381 Immunization by inoculation of DNA transcription unit

Patent 6841381 was granted and assigned to University of Massachusetts Medical School on January, 2005 by the United States Patent and Trademark Office.

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Patent
Patent
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Patent attributes

Patent Applicant
0
Current Assignee
University of Massachusetts Medical School
University of Massachusetts Medical School
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
68413810
Patent Inventor Names
Robert G. Webster0
Ellen F. Fynan0
Harriet L. Robinson0
Shan Lu0
Date of Patent
January 11, 2005
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Patent Application Number
081878790
Date Filed
January 27, 1994
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Patent Primary Examiner
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Dave T Nguyen
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Patent abstract

This invention relates to a method of immunizing a vertebrate, comprising introducing into the vertebrate a DNA transcription unit which comprises DNA encoding a desired antigen or antigens. The uptake of the DNA transcription unit by a host vertebrate results in the expression of the desired antigen or antigens, thereby eliciting humoral or cell-mediated immune responses or both humoral and cell-mediated responses. The elicited humoral and cell-mediated immune response can provide protection against infection by pathogenic agents, provide an anti-tumor response, or provide contraception. The host can be any vertebrate, avian or mammal, including humans.

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