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US Patent 12134658 Materials and methods for multidirectional biotransportation in virotherapeutics

Patent 12134658 was granted and assigned to Janssen Biotech on November, 2024 by the United States Patent and Trademark Office.

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Patent attributes

Patent Applicant

Janssen Biotech

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Current Assignee

Janssen Biotech

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Rajitha Doddareddy0

Sanjaya Singh0

Ninkka Tamot0

Ian White0

Paul B. Harvilla0

Adam Zwolak0

Martin Jack Borrok, III0

Rajkumar Ganesan0

Date of Patent

November 5, 2024

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Patent Application Number

173917440

Date Filed

August 2, 2021

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Patent Citations

US Patent 9718872 Human antibodies to middle east respiratory syndrome—coronavirus spike protein

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US Patent 9409989 Method for making multispecific antibodies having heteromultimeric and common components

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US Patent 6989250 Method for in vitro molecular evolution of protein function

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US Patent 7404954 Methods of targeting agents to cells expressing the polymeric immunoglobulin receptor

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US Patent 7612181 Dual variable domain immunoglobulin and uses thereof

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US Patent 7985840 Synthetic antibody phage libraries

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US Patent 8685897 Methods of generating libraries and uses thereof

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Patent Primary Examiner

Aurora M Fontainhas

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CPC Code

0

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Patent abstract

Provided herein are multispecific molecules comprising a first binding domain that specifically binds to polymeric immunoglobulin receptor (pIgR) and a second binding domain that specifically binds to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and related methods for the treatment of patients infected with SARS-CoV-2.

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