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US Patent 12122823 Isoform-selective TGFB1 inhibitors and use thereof

Patent 12122823 was granted and assigned to Scholar Rock on October, 2024 by the United States Patent and Trademark Office.

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Patent abstract

Disclosed herein are monoclonal antibodies and antigen-binding fragments thereof capable of selectively inhibiting TGFβ1 with high potency. Related compositions, methods and therapeutic use are also disclosed.

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