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US Patent 12116640 Methods for early detection of cancer

Patent 12116640 was granted and assigned to Guardant Health on October, 2024 by the United States Patent and Trademark Office.

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 US Patent 12116640 Methods for early detection of cancer

Article

Patent abstract

Disclosed herein are methods, compositions, and devices for use in the early detection of cancer. The methods include preparing cell-free nucleic acid molecules from a subject for sequencing, sequencing a panel of regions in the cell-free nucleic acid molecules, and detecting one or more markers that are indicative of a cancer.

Infobox
Is a
Patent
Patent
0
Patent Applicant
Guardant Health
Guardant Health
0
Current Assignee
Guardant Health
Guardant Health
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
121166400
Patent Inventor Names
AmirAli Talasaz0
Darya Chudova0
Helmy Eltoukhy0
Stefanie Ann Ward Mortimer0
Date of Patent
October 15, 2024
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Patent Application Number
184368210
Date Filed
February 8, 2024
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Patent Citations
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US Patent 7537897 Molecular counting
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US Patent 7723103 Vectors, kits and methods for cloning DNA
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US Patent 7803929 Kits for diagnosis and monitoring of pathogenic infection by analysis of cell-free pathogenic nucleic acids in urine
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US Patent 8420319 Asymmetric adapter library construction
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US Patent 8603749 Multitag sequencing ecogenomics analysis-US
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US Patent 8741606 Method of tagging using a split DBR
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US Patent 8835358 Digital counting of individual molecules by stochastic attachment of diverse labels
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US Patent 8999634 Nucleic acid detection combining amplification with fragmentation
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US Patent 9018365 Methods and compositions for tagging and identifying polynucleotides
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US Patent 9080210 High throughput screening using combinatorial sequence barcodes
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US Patent 9260753 Single cell nucleic acid detection and analysis
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US Patent 9404156 Varietal counting of nucleic acids for obtaining genomic copy number information
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US Patent 9745627 High throughput screening of populations carrying naturally occurring mutations
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US Patent 9752188 Methods of lowering the error rate of massively parallel DNA sequencing using duplex consensus sequencing
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US Patent 9850523 Methods for multi-resolution analysis of cell-free nucleic acids
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US Patent 10450611 Personalized genetic testing
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US Patent 10577650 Compositions and methods for identifying nucleic acid molecules
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US Patent 10597717 Combinatorial DNA screening
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US Patent 11319593 Distinguishing methylation levels in complex biological samples
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US Patent 11345968 Methods for computer processing sequence reads to detect molecular residual disease
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US Patent 11359248 Methods for detecting single nucleotide variants or indels by deep sequencing
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US Patent 11384382 Methods of attaching adapters to sample nucleic acids
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US Patent 11408033 Methods and systems for genetic analysis
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US Patent 11408037 Detecting mutations and ploidy in chromosomal segments
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US Patent 11519039 Methods for computer processing sequence reads to detect molecular residual disease
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US Patent 11525162 Methods for simultaneous amplification of target loci
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US Patent 11530454 Detecting mutations and ploidy in chromosomal segments
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US Patent 11643694 Methods for early detection of cancer
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US Patent 11773453 Systems and methods to detect rare mutations and copy number variation
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US Patent 11788153 Methods for early detection of cancer
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US Patent 11932910 Combinatorial DNA screening
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Patent Primary Examiner
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Cynthia B Wilder
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CPC Code
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C12M 1/00
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C12M 1/34
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G01N 33/57407
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G16H 50/30
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G16H 50/20
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G16B 30/10
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G16B 20/20
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C12Q 2600/166
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C12Q 2600/158
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C12Q 2600/156
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C12Q 2600/154
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C12Q 2600/118
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C12Q 1/6886
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C12Q 1/6869
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C12Q 1/6855
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C12Q 1/6806
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