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US Patent 12110513 Engineered pantothenate kinase variant enzymes

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Is a
Patent
Patent
0

Patent attributes

Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
0
Patent Number
121105130
Patent Inventor Names
Anna Fryszkowska0
Margie Tabuga Borra-Garske0
Grant Murphy0
Oscar Alvizo0
Agustina Rodriguez-Granillo0
Aksiniya Lyubenova Petkova0
Lillian Jasmine Miller0
Jesse B. Slaton0
...
Date of Patent
October 8, 2024
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Patent Application Number
171206460
Date Filed
December 14, 2020
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Patent Citations
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US Patent 7384387 High throughput mass spectrometry
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US Patent 8058001 Oligonucleotide mediated nucleic acid recombination
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US Patent 8076138 Evolution of whole cells and organisms by recursive sequence recombination
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US Patent 8108150 Optimization of crossover points for directed evolution
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US Patent 8170806 Methods of populating data structures for use in evolutionary simulations
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US Patent 8224580 Optimization of crossover points for directed evolution
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US Patent 8377681 Evolution of whole cells and organisms by recursive sequence recombination
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US Patent 8383346 Combined automated parallel synthesis of polynucleotide variants
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...
Patent Primary Examiner
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Paul J Holland
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CPC Code
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C12N 9/1205
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C12Y 207/01083
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Patent abstract

The present invention provides engineered pantothenate kinase (PanK) enzymes, polypeptides having PanK activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing PanK enzymes are also provided. The present invention further provides compositions comprising the PanK enzymes and methods of using the engineered PanK enzymes. The present invention finds particular use in the production of pharmaceutical compounds.

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