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US Patent 12110337 Anti-CD27 antibodies and uses thereof

Patent 12110337 was granted and assigned to Bristol-Myers Squibb Company on October, 2024 by the United States Patent and Trademark Office.

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Is a
Patent
Patent
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Patent attributes

Patent Applicant
Bristol-Myers Squibb Company
Bristol-Myers Squibb Company
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Current Assignee
Bristol-Myers Squibb Company
Bristol-Myers Squibb Company
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
121103370
Patent Inventor Names
Guodong Chen0
Li-Sheng Lu0
Mohan Srinivasan0
Haichun Huang0
Jun Zhang0
Ekaterina Deyanova0
Mark J. Selby0
Shrikant Deshpande0
...
Date of Patent
October 8, 2024
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Patent Application Number
170451430
Date Filed
April 3, 2019
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Patent Citations
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US Patent 9527916 Agonistic antibody to CD27
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US Patent 7943743 Human monoclonal antibodies to programmed death ligand 1 (PD-L1)
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US Patent 8008449 Human monoclonal antibodies to programmed death 1 (PD-1) and methods for treating cancer using anti-PD-1 antibodies alone or in combination with other immunotherapeutics
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US Patent 8217149 Anti-PD-L1 antibodies, compositions and articles of manufacture
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US Patent 9683046 Nucleic acid molecules encoding anti-CD27 antibodies
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Patent Primary Examiner
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Claire Kaufman
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Patent abstract

This disclosure provides isolated antibodies that bind specifically to CD27 with high affinity. The disclosure provides methods for treating a subject afflicted with a cancer comprising administering to the subject a therapeutically effective amount of an anti-CD27 antibody as monotherapy or in combination with a checkpoint inhibitor, such as an anti-PD-1, anti-PD-L1, or anti-CTLA-4 antibody.

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