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US Patent 12105084 Nucleic acid linked immune-sandwich assay (NULISA)

Patent 12105084 was granted and assigned to Alamar Biosciences, Inc. on October, 2024 by the United States Patent and Trademark Office.

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Contents

Is a
Patent
Patent
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Patent attributes

Patent Applicant
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Alamar Biosciences, Inc.
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Current Assignee
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Alamar Biosciences, Inc.
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
121050840
Patent Inventor Names
Wei Feng0
Yuling Luo0
Shiping Chen0
Adrian Grzybowski0
Yiyuan Yin0
Date of Patent
October 1, 2024
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Patent Application Number
173303310
Date Filed
May 25, 2021
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Patent Citations
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US Patent 7074564 Rolling circle replication of padlock probes
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US Patent 7078173 Assays and therapies for latent viral infection
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US Patent 7122313 Methods and kits for identifying and quantifying RNAs and DNAs associated with RNA and DNA binding proteins
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US Patent 7148043 Systems and methods for fluorescence detection with a movable detection module
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US Patent 7211710 Grapevine fanleaf virus resistance in grapevine
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US Patent 7214546 Dendritic chemiluminescent substrates
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US Patent 7294460 Supported double layer structure for displaying a nucleic acid associated with a protein
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US Patent 7306904 Methods and kits for proximity probing
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...
Patent Primary Examiner
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Steven Pohnert
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CPC Code
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G01N 33/54306
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G01N 33/6872
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G01N 2333/71
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C12Q 1/6813
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Patent abstract

Disclosed herein are highly sensitive immunoassays that utilize a capture/release mechanism to reduce non-specific binding and achieve detection with attomolar-level sensitivity. Kits that can be used for carrying out these highly sensitive immunoassays are also disclosed herein.

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