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US Patent 12091662 Compositions for modulating tau expression

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 US Patent 12091662 Compositions for modulating tau expression

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Patent abstract

Disclosed herein are antisense compounds and methods for decreasing Tau mRNA and protein expression. Such methods, compounds, and compositions are useful to treat, prevent, or ameliorate Tau-associated diseases, disorders, and conditions.

Infobox
Is a
Patent
Patent
0
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
0
Patent Number
120916620
Patent Inventor Names
Eric E. Swayze0
Holly Kordasiewicz0
Huynh-Hoa Bui0
Susan M. Freier0
Date of Patent
September 17, 2024
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Patent Application Number
181559450
Date Filed
January 18, 2023
0
Patent Citations
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US Patent 7217805 Bicyclonucleoside analogues
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US Patent RE44779 Bicyclonucleoside and oligonucleotide analogues
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US Patent 8871729 Treatment of CNS conditions
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US Patent 9012421 Bicyclic cyclohexose nucleic acid analogs
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US Patent 9084813 Agents that reduce neuronal overexcitation
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US Patent 9198982 Agents that reduce neuronal overexcitation
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US Patent 9644207 Compositions and methods for modulating Tau expression
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US Patent 9683235 Compositions for modulating Tau expression
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US Patent 10273474 Methods for modulating Tau expression for reducing seizure and modifying a neurodegenerative syndrome
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US Patent 10407680 Compounds and methods for reducing Tau expression
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US Patent 10793856 Compositions for modulating Tau expression
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US Patent 11591595 Compositions for modulating Tau expression
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US Patent 11781135 Methods for treating Alzheimer's disease
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US Patent 7034133 Oligonucleotide analogues
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US Patent 7053207 L-ribo-LNA analogues
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US Patent 7084125 Xylo-LNA analogues
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Patent Primary Examiner
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Sean McGarry
0

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