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US Patent 12084655 Packaging oligonucleotides into virus-like particles

Patent 12084655 was granted and assigned to Checkmate Pharmaceuticals on September, 2024 by the United States Patent and Trademark Office.

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Is a
Patent
Patent
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Patent attributes

Patent Applicant
Checkmate Pharmaceuticals
Checkmate Pharmaceuticals
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Current Assignee
Checkmate Pharmaceuticals
Checkmate Pharmaceuticals
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
120846550
Patent Inventor Names
Evan David Walters0
Frank Hennecke0
Date of Patent
September 10, 2024
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Patent Application Number
170459290
Date Filed
April 8, 2019
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Patent Citations
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US Patent 7517520 Packaging of immunostimulatory oligonucleotides into virus-like particles: method of preparation and use
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US Patent 7521063 Multiple CPG oligodeoxynucleotides and their use to induce an immune response
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US Patent 7566703 Semi-soft C-class immunostimulatory oligonucleotides
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US Patent 7605238 Human CTLA-4 antibodies and their uses
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US Patent 7635468 Allogeneic tumor therapeutic agent, a vaccine using allogeneic tumor cells for the therapeutic treatment of tumor diseases, and a method for the making of such a vaccine, and transfected human tumor cells for use as a vaccine
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US Patent 7776344 Methods related to immunostimulatory nucleic acid-induced interferon
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US Patent 7795235 Semi-soft c-class immunostimulatory oligonucleotides
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US Patent 7888098 Scalable process for protein purification
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...
Patent Primary Examiner
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Patrick T. Lewis
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Patent abstract

The present invention relates to processes for producing compositions comprising (i) a virus-like particle of an RNA bacteriophage, and (ii) aggregated oligonucleotides, wherein said aggregated oligonucleotides are packaged into said virus-like particle. The invention further provides processes for producing nucleotide compositions comprising aggregated oligonucleotides suitable for use in the aforementioned processes before. Moreover, the invention further provides nucleotide compositions comprising aggregated oligonucleotides. Furthermore, the invention further provides compositions comprising (i) a virus-like particle of an RNA bacteriophage, and (ii) aggregated oligonucleotides, wherein said aggregated oligonucleotides are packaged into said virus-like particle.

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