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US Patent 12084453 Bicyclic amines as CDK12 inhibitors

Patent 12084453 was granted and assigned to Incyte on September, 2024 by the United States Patent and Trademark Office.

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Is a

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Patent attributes

Patent Applicant

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Current Assignee

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Oleg Vechorkin0

Xin Li0

Hai Fen Ye0

Minh Nguyen0

Date of Patent

September 10, 2024

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Patent Application Number

180641730

Date Filed

December 9, 2022

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Patent Citations

US Patent 8168757 PD-1 binding proteins

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US Patent 8217149 Anti-PD-L1 antibodies, compositions and articles of manufacture

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US Patent 9828373 2-amino-pyrido[2,3-D]pyrimidin-7(8H)-one derivatives as CDK inhibitors and uses thereof

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US Patent 9670202 Substituted triazolopyridines

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US Patent 10059690 Inhibitors of cyclin-dependent kinase 7 (CDK7)

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US Patent 10106526 Inhibitors of cyclin-dependent kinase 7 (CDK7)

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US Patent 10111875 Pyrrolopyrimidine compounds and uses thereof

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US Patent 10519135 Inhibitors of cyclin-dependent kinase 7 (CDK7)

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Patent Primary Examiner

Joseph R Kosack

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Patent abstract

The present application provides bicyclic amines that are inhibitors of cyclin-dependent kinase 12 (CDK12), as well as pharmaceutical compositions thereof, and methods of treating cancer using the same.

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