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US Patent 12083169 Alkaline phosphatase polypeptides and methods of use thereof

Patent 12083169 was granted and assigned to Alexion Pharmaceuticals on September, 2024 by the United States Patent and Trademark Office.

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Patent attributes

Patent Applicant

Alexion Pharmaceuticals

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Current Assignee

Alexion Pharmaceuticals

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Yang Guo0

Eric Falcone0

Jonathan Monteleone0

Tatyana Mezhebovsky0

Yuhong Wu0

Walter C. Voegtli0

Date of Patent

September 10, 2024

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Patent Application Number

176692750

Date Filed

February 10, 2022

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US Patent 6905689 Conjugate of a tissue non-specific alkaline phosphatase and dextran, process for its production and use thereof

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Patent Primary Examiner

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Patent abstract

Featured are pharmaceutical compositions that include a soluble alkaline phosphatase for treating bone mineralization disorders, such as hypophosphatasia (HPP), and symptoms thereof. The polypeptides include a soluble alkaline phosphatase (sALP) or fragment thereof, which is derived from a naturally occurring alkaline phosphatase (ALP).

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