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US Patent 12077725 Ionizable cationic lipids

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Patent
Patent
0

Patent attributes

Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
0
Patent Number
120777250
Patent Inventor Names
Dmitri B. Kirpotin0
Daryl C. Drummond0
Mark E. Hayes0
Date of Patent
September 3, 2024
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Patent Application Number
180645650
Date Filed
December 12, 2022
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Patent Citations
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US Patent 9657295 Modified nucleosides, nucleotides, and nucleic acids, and uses thereof
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US Patent 10221127 Lipids and lipid nanoparticle formulations for delivery of nucleic acids
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US Patent 10369226 Biodegradable lipids for the delivery of active agents
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US Patent 10632191 Synthetic glucopyranosyl lipid adjuvants
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US Patent 10653780 Amino lipids and methods for the delivery of nucleic acids
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US Patent 11071784 Biodegradable lipids for the delivery of active agents
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US Patent 11246933 Biodegradable lipids for the delivery of active agents
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US Patent 11591544 Ionizable cationic lipids
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...
Patent Primary Examiner
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Taofiq A. Solola
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CPC Code
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C11C 3/003
0
Patent abstract

The present disclosure provides compounds useful as ionizable cationic lipids. The ionizable cationic lipids are useful for preparing lipid nanoparticles for the delivery of therapeutic nucleic acids to cells. Cationic ionizable lipids were engineered with improved stability to oxidative degradation while in storage.

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