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US Patent 12070449 Methods of treating TTR amyloidosis using AG10

Patent 12070449 was granted and assigned to Eidos Therapeutics on August, 2024 by the United States Patent and Trademark Office.

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 US Patent 12070449 Methods of treating TTR amyloidosis using AG10

Article

Patent abstract

Described herein are methods for treating transthyretin (TTR) amyloidosis in a subject. The methods include specific dosing regimens that have great efficacy in treating the subjects and that are well tolerated in subjects

Infobox
Is a
Patent
Patent
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Patent Applicant
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Eidos Therapeutics
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Current Assignee
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Eidos Therapeutics
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
120704490
Patent Inventor Names
Satish Rao0
Uma Sinha0
Date of Patent
August 27, 2024
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Patent Application Number
173323590
Date Filed
May 27, 2021
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Patent Citations
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US Patent 11078162 Processes for preparing AG-10, its intermediates, and salts thereof
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US Patent 7763747 Compounds, compositions and methods for the treatment of amyloid diseases and synucleinopathies such as alzheimer's disease, type 2 diabetes, and parkinson's disease
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US Patent 8143424 Thyroid like compounds
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US Patent 8168775 Compositions and methods for inhibiting expression of transthyretin
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US Patent 8226977 Pharmaceutical composition containing irbesartan
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US Patent 8378118 Pyrazole-based thyroid receptor compounds
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US Patent 8552034 Pharmaceutical compositions of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid and administration thereof
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US Patent 8642660 Method for altering the lifespan of eukaryotic organisms
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US Patent 8877795 Identification of stabilizers of multimeric proteins
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US Patent 9169214 Compounds and compositions that bind and stabilize transthyretin and their use for inhibiting transthyretin amyloidosis and protein-protein interactions
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US Patent 9308209 Identification of stabilizers of multimeric proteins
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US Patent 9642838 Compounds and compositions that bind and stabilize transthyretin and their use for inhibiting transthyretin amyloidosis and protein-protein interactions
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US Patent 9913826 Compounds and compositions that bind and stabilize transthyretin and their use for inhibiting transthyretin amyloidosis and protein-protein interactions
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US Patent 10039726 Identification of stabilizers of multimeric proteins
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US Patent 10278929 Identification of stabilizers of multimeric proteins
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US Patent 10398681 Compounds and compositions that bind and stabilize transthyretin and their use for inhibiting transthyretin amyloidosis and protein-protein interactions
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US Patent 10513497 Process for preparing AG-10, its intermediates, and salts thereof
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US Patent 10842777 Compounds and compositions that bind and stabilize transthyretin and their use for inhibiting transthyretin amyloidosis and protein-protein interactions
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US Patent 11058668 Methods of treating TTR amyloidosis using AG10
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US Patent 11260047 Formulations of AG10
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Patent Primary Examiner
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Svetlana M Ivanova
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CPC Code
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A61K 31/415
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