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US Patent 12064429 Substituted 5-fluoro-1H-pyrazolopyridines and their use

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Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Donald Bierer0

Gorden Redlich0

Andreas Knorr0

Volkhart Min-Jian Li0

Markus Follmann0

Jens Ackerstaff0

Elke Hartmann0

Rolf Jautelat0

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Date of Patent

August 20, 2024

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Patent Application Number

178206670

Date Filed

August 18, 2022

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Patent Citations

US Patent 7226941 Compound for treating angiogenesis

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US Patent 8309551 Pyrazolopyridine, indazole, imidazopyridine, imidazopyrimidine, pyrazolopyrazine and pyrazolopyridine derivatives as stimulators of guanylate cyclase for cardiovascular disorders

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US Patent 8334291 Aliphatically substituted pyrazolopyridines, and the use thereof

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US Patent 8420656 Substituted 5-fluoro-1H-pyrazolopyridines and their use

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US Patent 8492544 Process for preparing methyl {4,6-diamino-2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-B]pyridin-3-yl]pyrimidin-5-yl}Methylcarbamate and its purification for use as pharmaceutically active compound

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US Patent 8501945 Process for preparing methyl {4,6-diamino-2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl}carbamate and its purification for use as pharmaceutically active compound

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US Patent 8802847 Process for preparing substituted 5-fluoro-1H-pyrazolopyridines

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US Patent 8853398 Process for preparing methyl {4,6-diamino-2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b] pyridin-3-yl]pyrimidin-5-yl}methylcarbamate and its purification for use as pharmaceutically active compound

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Patent abstract

The present application relates to novel substituted 5-fluoro-1H-pyrazolopyridines, to processes for their preparation, to their use alone or in combinations for the treatment and/or prophylaxis of diseases, and to their use for producing medicaments for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of cardiovascular disorders.

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