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US Patent 12059413 Methods of inhibiting viruses using compositions targeting TSG101-ubiquitin interaction

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Contents

Is a
Patent
Patent
0

Patent attributes

Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
120594130
Patent Inventor Names
Nico Tjandra0
Carol Carter0
Madeleine Davison0
Lorna Erlich0
Date of Patent
August 13, 2024
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Patent Application Number
163426950
Date Filed
October 30, 2017
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Patent Citations
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US Patent 7750134 Nucleic acids encoding microbial SUMO protease homologs
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US Patent 10765687 Methods and compounds to inhibit enveloped virus release
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US Patent 10806737 Compounds and methods for the targeted degradation of fetal liver kinase polypeptides
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US Patent 10864248 Dab2 inhibitors for the prevention and treatment of cystic fibrosis
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US Patent 10954287 Ras binding peptides and methods of use
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US Patent 11028088 Modulators of BTK proteolysis and methods of use
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US Patent 11065231 Compounds and methods for the targeted degradation of interleukin-1 receptor- associated kinase 4 polypeptides
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US Patent 11191741 Compounds and methods for the targeted degradation of enhancer of zeste homolog 2 polypeptide
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...
Patent Primary Examiner
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Savitha M Rao
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CPC Code
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A61P 31/12
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Y02A 50/30
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G01N 33/56983
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G01N 33/56988
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A61K 31/4439
0
Patent abstract

The present invention provides a method of inhibiting release of a virus from a cell, comprising contacting the cell with a compound that binds an ubiquitin E2 variant (UEV) domain of a cellular polypeptide, or fragment thereof, with an affinity sufficient to inhibit or disrupt the binding of the cellular polypeptide, or fragment thereof, to ubiquitin.

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