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US Patent 12011481 Anti-TIM-3 antibodies and methods of use thereof

Patent 12011481 was granted and assigned to Agenus on June, 2024 by the United States Patent and Trademark Office.

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Contents

Is a
Patent
Patent
0

Patent attributes

Patent Applicant
Agenus
Agenus
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Current Assignee
Agenus
Agenus
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
120114810
Patent Inventor Names
Ekaterina Vladimirovna Breous-Nystrom0
Dennis John Underwood0
Jeremy Dale Waight0
Nicholas Stuart Wilson0
Marc van Dijk0
Date of Patent
June 18, 2024
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Patent Application Number
171472520
Date Filed
January 12, 2021
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Patent Citations
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US Patent 8591886 Combination therapies employing GITR binding molecules
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US Patent 8697069 Methods related to TIM 3, a Th1-specific cell surface molecule, for activating antigen presenting cells
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US Patent 8709412 Modulation of TIM receptor activity in combination with cytoreductive therapy
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US Patent 8709715 Cytokine receptors associated with myelogenous haematological proliferative disorders and uses thereof
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US Patent 9132281 Focused radiation for augmenting immune-based therapies against neoplasms
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US Patent 9163087 Bi-specific antibodies against TIM-3 and PD-1 for immunotherapy in chronic immune conditions
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US Patent 9333256 Methods related to TIM 3, a Th1-specific cell surface molecule, for activating antigen presenting cells
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US Patent 9605070 Antibody molecules to TIM-3 and uses thereof
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...
Patent Primary Examiner
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Lynn A Bristol
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CPC Code
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C07K 2317/565
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Patent abstract

The instant disclosure provides antibodies that specifically bind to TIM 3 and antagonize TIM-3 function. Also provided are pharmaceutical compositions comprising these antibodies, nucleic acids encoding these antibodies, expression vectors and host cells for making these antibodies, and methods of treating a subject using these antibodies.

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