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US Patent 12006368 Anti-frizzled antibodies and methods of use

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 US Patent 12006368 Anti-frizzled antibodies and methods of use

Article

Patent abstract

The present invention provides anti-Fzd monoclonal antibodies and related compositions, which may be used in any of a variety of therapeutic methods for the treatment of diseases.

Infobox
Is a
Patent
Patent
0
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
0
Patent Number
120063680
Patent Inventor Names
Aaron Ken Sato0
Chenggang Lu0
Claudia Yvonne Janda0
Parthasarathy Sampathkumar0
Tom Zhiye Yuan0
Wen-Chen Yeh0
Yang Li0
Date of Patent
June 11, 2024
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Patent Application Number
169544820
Date Filed
December 19, 2018
0
Patent Citations
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US Patent 7297775 Polypeptide variants
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US Patent 7317091 Optimized Fc variants
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US Patent 7364731 Polypeptide variants
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US Patent 7657380 Methods of generating variant antibodies with increased host string content
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US Patent 7662925 Optimized Fc variants and methods for their generation
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US Patent 7982013 Frizzled-binding agents and uses thereof
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US Patent 8202966 Human Dickkopf-related protein and nucleic acid molecules and uses therefor
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US Patent 8221751 Tumor-targeting monoclonal antibodies to FZD10 and uses thereof
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US Patent 8343922 Compositions and methods for the stimulation or enhancement of bone formation and the self-renewal of cells
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US Patent 8461155 Sclerostin and the inhibition of WNT signaling and bone formation
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US Patent 8507442 Methods of use for an antibody against human frizzled receptors 1, 2. 5, 7 or 8
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US Patent 8637506 Compositions and methods for bone formation and remodeling
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US Patent 8715941 Antibodies to LRP6
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US Patent 8846041 Anti-LRP6 antibodies
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US Patent 8859736 Monoclonal antibodies that inhibit the wnt signaling pathway and methods of production and use thereof
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US Patent 8883735 Low density lipoprotein-related protein 6 (LRP6)-half life extender constructs
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US Patent 8975044 Polynucleotides encoding for frizzled-binding agents and uses thereof
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US Patent 9359444 Methods and monitoring of treatment with a Wnt pathway inhibitor
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US Patent 9573998 Antibodies against human FZD5 and FZD8
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US Patent 6838254 Production of antibodies or (functionalized) fragments thereof derived from heavy chain immunoglobulins of camelidae
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Patent Primary Examiner
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Marianne P Allen
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