Systems and methods are provided for dynamically protecting transportable articles in vehicles. A system for dynamically protecting a transportable article in a vehicle may include one or more processors and non-volatile memory storing instructions. The instructions, when executed by the one or more processors, cause the system to determine at least one of a characteristic or a trait of the transportable article; detect, based on sensed data, an emergency condition; select one or more article protection components based on (i) the at least one of the characteristic or the trait of the transportable article, and (ii) the detected emergency condition; and in response to detecting the emergency condition, deploy the selected one or more article protection components to protect the transportable article.