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US Patent 11999789 Humanized antibodies to TNF-like ligand 1A (TL1A) and uses thereof

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Is a

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Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Bradley Henkle0

Janine Bilsborough0

Jeffry D. Watkins0

Rafael Rojas0

Patricia McNeeley0

Cindy T. Dickerson0

Matthew Reissman0

Stephan R. Targan0

Date of Patent

June 4, 2024

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Patent Application Number

176829220

Date Filed

February 28, 2022

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Patent Citations

US Patent 8409577 Single chain multivalent binding proteins with effector function

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US Patent 8883975 Antibodies against IL-18R1 and uses thereof

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US Patent 9017679 Immunomodulating tumor necrosis factor receptor 25 (TNFR25) agonists, antagonists, and immunotoxins

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US Patent 9068003 Antibodies that bind to TL1A and methods of treating inflammatory or autoimmune disease comprising administering such antibodies

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US Patent 9102733 Anti-OX40L antibodies

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US Patent 9290576 Antibodies that bind to TL1A and their uses

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US Patent 9416185 Humanized antibodies against TL1A

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US Patent 9499627 Method for in vivo expansion of T regulatory cells

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Patent Primary Examiner

Bridget E Bunner

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CPC Code

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Patent abstract

Described herein are humanized anti-TL1A antibodies and pharmaceutical compositions for the treatment of inflammatory bowel disease (IBD), such as Crohn's Disease (CD) and ulcerative colitis (UC).

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