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US Patent 11986517 Cancer vaccines targeting mesothelin and uses thereof

Patent 11986517 was granted and assigned to Inovio Pharmaceuticals on May, 2024 by the United States Patent and Trademark Office.

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Contents

Is a
Patent
Patent
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Patent attributes

Patent Applicant
Inovio Pharmaceuticals
Inovio Pharmaceuticals
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Current Assignee
Inovio Pharmaceuticals
Inovio Pharmaceuticals
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
119865170
Patent Inventor Names
Neil Cooch0
Bradley Garman0
Anna Slager0
Jian Yan0
Date of Patent
May 21, 2024
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Patent Application Number
174677280
Date Filed
September 7, 2021
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Patent Citations
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US Patent 8008265 Vaccines, immunotherapeutics and methods for using the same
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US Patent 8119395 Vaccines, immunotherapeutics and methods for using the same
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US Patent 8173786 Nucleic acid sequences encoding and compositions comprising IgE signal peptide and/or IL-15 and methods for using the same
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US Patent 8178660 Vaccines and immunotherapeutics using codon optimized IL-15 and methods for using the same
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US Patent 10071154 Vaccines and immunotherapeutics using IL-28 and compositions and methods of using the same
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US Patent 9452285 Electroporation devices and methods of using same for electroporation of cells in mammals
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US Patent 6939862 Method for transferring nucleic acid into striated muscles
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US Patent 6958060 Method for muscle delivery of drugs, nucleic acids and other compounds
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...
Patent Primary Examiner
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Yan Xiao
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CPC Code
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A61P 35/00
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A61K 2039/55538
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A61K 39/39
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A61K 39/001168
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Patent abstract

Disclosed herein are nucleic acid molecules comprising one or more nucleic acid sequences that encode a modified consensus mesothelin antigen. Vectors, compositions, and vaccines comprising one or more nucleic acid sequences that encode a modified consensus mesothelin antigen are disclosed. Methods of treating a subject with a mesothelin-expressing tumor and methods of preventing a mesothelin-expressing tumor are disclosed. Modified consensus mesothelin antigen is disclosed.

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