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US Patent 11981745 Anti-mesothelin antigen-binding molecules and uses thereof

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Patent
Patent
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Patent attributes

Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
0
Patent Number
119817450
Patent Inventor Names
Ashok Bandaranayake0
Christopher Mehlin0
David Meininger0
Colin Correnti0
Date of Patent
May 14, 2024
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Patent Application Number
181636590
Date Filed
February 2, 2023
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Patent Citations
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US Patent 8357783 Human anti-mesothelin monoclonal antibodies
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US Patent 8460660 Anti-mesothelin antibodies
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US Patent 8911732 Anti-mesothelin antibodies and immunoconjugates
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US Patent 9023351 Anti-mesothelin antibodies and uses thereof
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US Patent 9416190 Mesothelin antibodies and methods for eliciting potent antitumor activity
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US Patent 9803022 Mesothelin domain-specific monoclonal antibodies and use thereof
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US Patent 10793641 Fully human anti-mesothelin antibodies and immune effector cells targeting mesothelin
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US Patent 10100121 Anti-mesothelin binding proteins
0
...
Patent Primary Examiner
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Michael Allen
0
Patent abstract

The present disclosure provides antibodies and polypeptides that specifically bind to mesothelin (MSLN), including bispecific antibodies that bind both MSLN and a T cell antigen (e.g., CD3). Also provided are pharmaceutical compositions comprising these antibodies, nucleic acids encoding these antibodies, expression vectors and host cells for making these antibodies, and methods of treating a subject using these antibodies.

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