Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Sean Higgins0
Gayathri Vijayakumar0
Trent Gomberg0
Angus Sidore0
Sarah Denny0
Brett T. Staahl0
Jason Fernandes0
Isabel Colin0
...
Date of Patent
May 7, 2024
0Patent Application Number
181641380
Date Filed
February 3, 2023
0Patent Citations
Patent Primary Examiner
Patent abstract
Provided herein are delivery particle systems (XDP) useful for the delivery of payloads of any type. In some embodiments, a XDP particle system with tropism for target cells of interest is used to deliver CRISPR/Cas polypeptides (e.g., CasX proteins) and guide nucleic acids (gNA), for the modification of nucleic acids in target cells. Also provided are methods of making and using such XDP to modify the nucleic acids in such cells.
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