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US Patent 11975026 CD19 and CD22 chimeric antigen receptors and uses thereof

Patent 11975026 was granted and assigned to Novartis on May, 2024 by the United States Patent and Trademark Office.

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Is a
Patent
Patent
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Patent attributes

Patent Applicant
Novartis
Novartis
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Current Assignee
Novartis
Novartis
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
119750260
Patent Inventor Names
Carla Patricia Guimaraes0
Boris Engels0
Date of Patent
May 7, 2024
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Patent Application Number
171049610
Date Filed
November 25, 2020
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Patent Citations
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US Patent 7320787 Redirection of cellular immunity by protein tyrosine kinase chimeras
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US Patent 7446190 Nucleic acids encoding chimeric T cell receptors
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US Patent 7446191 DNA construct encoding CE7-specific chimeric T cell receptor
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US Patent 7514537 Chimeric immunoreceptor useful in treating human gliomas
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US Patent 7638326 Activation and expansion of T-cells using an engineered multivalent signaling platform
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US Patent 7741465 Chimeric receptor genes and cells transformed therewith
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US Patent 7745140 Activation and expansion of T-cells using an engineered multivalent signaling platform as a research tool
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US Patent 7754482 Artificial antigen presenting cells and uses therefor
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...
Patent Primary Examiner
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Allison M Fox
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Patent abstract

The present disclosure provides compositions and methods for treating diseases associated with expression of CD19 and/or CD22, e.g., by administering a recombinant T cell or natural killer (NK) cell comprising a CD22 CAR and a CD19 CAR as described herein. The disclosure also relates to CAR molecules specific to CD22 and/or CD19, methods of making a cell comprising the same and vectors encoding the same.

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