Blockchain-based technologies to facilitate traceability of products through their lifecycle, including design, development, manufacturing, supply chain, and use. The system provides transparent, secure traceability through product lifecycle, drawing insights from collected data and post-market activities. For example, the system could receive tracking data from a plurality of tracking sources along a product's lifecycle and generate one or more blocks in a blockchain to capture the tracking data from the plurality of tracking sources along the product's lifecycle in one or more distributed ledgers.