US Patent 11968975 Compositions and methods for storing liquid biospecimens

A lyoprotectant composition includes one or more lyoprotective carbohydrates comprising a non-reducing polysaccharide. The non-reducing polysaccharide may be dextranol. The one or more lyoprotective carbohydrates may include a non-reducing disaccharide. The lyoprotectant composition may be free of or substantially free of reducing sugars. The composition may be in the form of a matrix including a non-woven web of fibers having an average diameter of 0.1 μm to 2.5 μm. A method of storing a liquid biospecimen includes mixing the liquid biospecimen with the lyoprotectant composition to prepare a specimen-loaded composition; drying the specimen-loaded composition; and storing the dried specimen-loaded composition.