Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
George Georgiou0
Tae Hyun Kang0
Chang-Han Lee0
Date of Patent
April 16, 2024
0Patent Application Number
173466480
Date Filed
June 14, 2021
0Patent Citations
Patent Primary Examiner
Patent abstract
In some aspects, mutant or variant Fc domains are provided that exhibit increased binding to FcRn and increased half-life after administration in vivo. The Fc domain may be comprised in a glycosylated or aglycosylated antibody. Methods for using the mutant or variant Fc domains or polypeptides comprising the mutant or variant Fc domains are also provided.
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