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US Patent 11945840 Protein pores

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Contents

Is a
Patent
Patent
0

Patent attributes

Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
119458400
Patent Inventor Names
Nani Van Gerven0
John Joseph Kilgour0
Richard George Hambley0
Michael Jordan0
Elizabeth Jayne Wallace0
Lakmal Jayasinghe0
Han Remaut0
Sander Van Der Verren0
...
Date of Patent
April 2, 2024
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Patent Application Number
172050540
Date Filed
March 18, 2021
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Patent Citations
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US Patent 9222082 Hybridization linkers
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US Patent 10443097 Method of improving the movement of a target polynucleotide with respect to a transmembrane pore
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US Patent 10472673 Hetero-pores
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US Patent 10514378 Nanopore biosensors for detection of proteins and nucleic acids
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US Patent 10669581 Method for sequencing a heteropolymeric target nucleic acid sequence
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US Patent 10802015 Nanopore biosensors for detection of proteins and nucleic acids
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US Patent 10844432 Method of improving the movement of a target polynucleotide with respect to a transmembrane pore
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US Patent 10882889 Mutant lysenin pores
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...
Patent Primary Examiner
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Aradhana Sasan
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CPC Code
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C07K 14/245
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C07K 14/475
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C12Q 1/6869
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C07K 14/00
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B82Y 5/00
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B82Y 15/00
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G01N 33/6872
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Patent abstract

The present invention relates to novel protein pores and their uses in analyte detection and characterisation. The invention particularly relates to an isolated pore complex formed by a CsgG-like pore and a modified CsgF peptide, or a homologue or mutant thereof, thereby incorporating an additional channel constriction or reader head in the nanopore. The invention further relates to a transmembrane pore complex and methods for production of the pore complex and for use in molecular sensing and nucleic acid sequencing applications.

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