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US Patent 11884732 Proteins binding HER2, NKG2D and CD16

Patent 11884732 was granted and assigned to Dragonfly Therapeutics, Inc. on January, 2024 by the United States Patent and Trademark Office.

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 US Patent 11884732 Proteins binding HER2, NKG2D and CD16

Article

Patent abstract

Multi-specific binding proteins that bind HER2, the NKG2D receptor, and CD 16 are described, as well as pharmaceutical compositions and therapeutic methods useful for the treatment of cancer.

Infobox
Is a
Patent
Patent
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Patent Applicant
Dragonfly Therapeutics, Inc.
Dragonfly Therapeutics, Inc.
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Current Assignee
Dragonfly Therapeutics, Inc.
Dragonfly Therapeutics, Inc.
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
118847320
Patent Inventor Names
Ann F. Cheung0
Bianka Prinz0
Bradley M. Lunde0
Gregory P. Chang0
William Haney0
Date of Patent
January 30, 2024
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Patent Application Number
164865690
Date Filed
February 20, 2018
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Patent Citations
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US Patent 11124582 FLT3L-FC fusion proteins
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US Patent 7112324 CD 19×CD3 specific polypeptides and uses thereof
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US Patent 7235641 Bispecific antibodies
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US Patent 7575923 CD19xCD3 specific polypeptides and uses thereof
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US Patent 7635472 Pharmaceutical compositions comprising bispecific anti-cd3, anti-cd19 antibody constructs for the treatment of b-cell related disorders
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US Patent 7820166 Potent T cell modulating molecules
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US Patent 7879985 Antibodies against human NKG2D and uses thereof
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US Patent 7951917 Method for making multispecific antibodies having heteromultimeric and common components
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US Patent 8007796 Means and methods for the treatment of tumorous diseases
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US Patent 8076459 Multispecfic deimmunized CD3-binders
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US Patent 8101722 Less immunogenic binding molecules
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US Patent 8236308 Composition comprising cross-species-specific antibodies and uses thereof
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US Patent 8409577 Single chain multivalent binding proteins with effector function
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US Patent 8518403 Expression-enhanced polypeptides
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US Patent 8591897 Anti-ERBB2 antibody adjuvant therapy
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US Patent 8658765 Non-natural MIC proteins
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US Patent 8784821 Human-anti-human cd3 binding molecules
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US Patent 8796420 Non-natural MIC proteins
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US Patent 8840888 Dosage regimen for administering a CD19XCD3 bispecific antibody
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US Patent 9079969 Non-natural MIC proteins
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US Patent 9102736 Multispecific deimmunized CD3-binders
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US Patent 9127064 Antibodies against human NKG2D and uses thereof
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US Patent 9150656 Antibodies reactive with B7-H3, immunologically active fragments thereof and uses thereof
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US Patent 9150663 Heterodimeric antibody Fc-containing proteins and methods for production thereof
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US Patent 9200078 Antibodies against prostate-specific stem cell antigen and use thereof
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US Patent 9248181 Methods and means for the production of Ig-like molecules
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US Patent 9248182 Methods and means for the production of Ig-like molecules
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US Patent 9273136 Fully human anti-human NKG2D monoclonal antibodies
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US Patent 9587036 Cross-species-specific PSMAxCD3 bispecific single chain antibody
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US Patent 9683053 Hetero-dimeric immunoglobulins
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US Patent 9718893 Bispecific antibody molecule
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US Patent 9951145 CH3 domain variant pair inducing formation of heterodimer of heavy chain constant region of antibody at high efficiency, method for preparing same, and use thereof
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US Patent 9963513 Method for the selection of antibodies against BCMA
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US Patent 10040853 Methods and compositions involving NKG2D inhibitors and cancer
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US Patent 10059765 Methods and compositions for increasing the efficiency of therapeutic antibodies using NK cell potentiating compounds
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US Patent 10377827 Antigen binding proteins that bind c-met
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US Patent 10526409 Antibodies against human NKG2D and uses thereof
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Patent Primary Examiner
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Nelson B Moseley, II
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CPC Code
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C07K 2317/94
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C07K 2317/732
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C07K 2317/71
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C07K 2317/64
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C07K 2317/569
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C07K 2317/565
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C07K 2317/52
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C07K 2317/53
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C07K 2317/524
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C07K 2317/33
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C07K 2317/31
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C07K 16/32
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C07K 16/2851
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C07K 16/283
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A61P 35/00
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