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US Patent 11883386 Prolyl hydroxylase inhibitors and methods of use

Patent 11883386 was granted and assigned to Akebia Therapeutics on January, 2024 by the United States Patent and Trademark Office.

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 US Patent 11883386 Prolyl hydroxylase inhibitors and methods of use

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Patent abstract

The present disclosure relates to HIF-1α prolyl hydroxylase inhibitors, compositions which comprise the HIF-1α prolyl hydroxylase inhibitors described herein and to methods for controlling, inter alia, Peripheral Vascular Disease (PVD), Coronary Artery Disease (CAD), heart failure, ischemia, and anemia.

Infobox
Is a
Patent
Patent
0
Patent Applicant
Akebia Therapeutics
Akebia Therapeutics
0
Current Assignee
Akebia Therapeutics
Akebia Therapeutics
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
118833860
Patent Inventor Names
Angelique Sun Boyer0
Artem G. Evdokimov0
Kenneth D Greis0
Namal C. Warshakoon0
Richard Masaru Kawamoto0
Shengde Wu0
Date of Patent
January 30, 2024
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Patent Application Number
178153910
Date Filed
July 27, 2022
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Patent Citations
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US Patent 7183287 Substituted pyrimidinones
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US Patent 7402696 Benzene compounds
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US Patent 7588824 Hydrogen cyano fullerene containing proton conducting membranes
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US Patent 7588924 Crystal of hypoxia inducible factor 1 alpha prolyl hydroxylase
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US Patent 7618940 Fat regulation
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US Patent 7811595 Prolyl hydroxylase inhibitors and methods of use
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US Patent 7897612 Substituted 1,8-naphthyridinecarboxamides for use as prolyl hydroxylase inhibitors
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US Patent 8050873 Crystal of hypoxia inducible factor 1 alpha prolyl hydroxylase
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US Patent 8124582 Treatment of diabetes
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US Patent 8323671 Prolyl hydroxylase inhibitors and methods of use
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US Patent 8343952 Prolyl hydroxylase inhibitors and methods of use
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US Patent 8512972 Crystal of hypoxia inducible factor 1 alpha prolyl hydroxylase
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US Patent 8530404 Compounds and methods for treatment of cancer
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US Patent 8598210 Prolyl hydroxylase inhibitors and methods of use
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US Patent 8722895 Prolyl hydroxylase inhibitors and method of use
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US Patent 8865748 Compounds and compositions for stabilizing hypoxia inducible factor-2 alpha as a method for treating cancer
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US Patent 8940773 Prolyl hydroxylase inhibitors and methods of use
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US Patent 9145366 Process for preparing [(3-hydroxypyridine-2-carbonyl)amino]alkanoic acids, esters and amides
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US Patent 9598370 Prolyl hydroxylase inhibitors and methods of use
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US Patent 9701636 Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino}acetic acid, compositions, and uses thereof
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US Patent 9776969 Process for preparing [(3-hydroxypyridine-2-carbonyl)amino]alkanoic acids, esters and amides
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US Patent 9987262 Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino}acetic acid, compositions, and uses thereof
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US Patent 10149842 Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino}acetic acid, compositions, and uses thereof
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US Patent 10150734 Solid forms of 2-(5-(3-fluorophenyl)-3-hydroxypicolinamido)acetic acid, compositions, and uses thereof
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US Patent 10246416 Process for preparing [(3-hydroxypyridine-2-carbonyl)amino] alkanoic acids, esters and amides
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US Patent 10596158 Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino}acetic acid, compositions, and uses thereof
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US Patent 10729681 Prolyl hydroxylase inhibitors and methods of use
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US Patent 10738010 Process for preparing [(3-hydroxypyridine-2-carbonyl)amino] alkanoic acids, esters and amides
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US Patent 11065237 Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino}acetic acid, compositions, and uses thereof
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US Patent 11267785 Process for preparing [(3-hydroxypyridine-2-carbonyl)amino]alkanoic acids, esters and amides
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US Patent 11426393 Prolyl hydroxylase inhibitors and methods of use
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US Patent 6855510 Pharmaceuticals and methods for treating hypoxia and screening methods therefor
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Patent Primary Examiner
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Daniel R Carcanague
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CPC Code
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C07D 213/81
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C07D 213/65
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