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US Patent 11878145 Closed loop control of physiological glucose

Patent 11878145 was granted and assigned to Ypsomed on January, 2024 by the United States Patent and Trademark Office.

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 US Patent 11878145 Closed loop control of physiological glucose

Article

Patent abstract

The present disclosure relates to systems and methods for controlling physiological glucose concentrations in a patient using a closed loop artificial pancreas. The systems and methods may utilize a controller with control logic operative to execute a multi-model predictive controller algorithm to determine a medication dose to the patient.

Infobox
Is a
Patent
Patent
0
Patent Applicant
Ypsomed
Ypsomed
0
Current Assignee
Ypsomed
Ypsomed
0
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
0
Patent Number
118781450
Patent Inventor Names
Ahmad Mohamad Haidar0
Date of Patent
January 23, 2024
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Patent Application Number
166080540
Date Filed
May 3, 2018
0
Patent Citations
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US Patent 7267665 Closed loop system for controlling insulin infusion
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US Patent 7278983 Physiological monitoring device for controlling a medication infusion device
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US Patent 7354420 Closed loop system for controlling insulin infusion
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US Patent 7389133 Method and device for continuous monitoring of the concentration of an analyte
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US Patent 7395216 Using predictive models to continuously update a treatment plan for a patient in a health care location
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US Patent 7399277 System for monitoring physiological characteristics
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US Patent 7402153 Closed-loop method for controlling insulin infusion
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US Patent 7491187 Automatic infusion system based on an adaptive patient model
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US Patent 7547281 Algorithm sensor augmented bolus estimator for semi-closed loop infusion system
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US Patent 7569030 Safety limits for closed-loop infusion pump control
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US Patent 7590443 System and method for detecting hypoglycemia based on a paced depolarization integral using an implantable medical device
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US Patent 7651845 Method and apparatus for glucose control and insulin dosing for diabetics
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US Patent 7704226 External infusion device with programmable capabilities to time-shift basal insulin and method of using the same
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US Patent 7727147 Method and system for implantable glucose monitoring and control of a glycemic state of a subject
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US Patent 7766830 System for monitoring physiological characteristics
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US Patent 7766831 System, tools, devices and a program for diabetes care
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US Patent 7778680 System and methods for processing analyte sensor data
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US Patent 7785313 Closed loop/semi-closed loop therapy modification system
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US Patent 7806854 Fully automated control system for type 1 diabetes
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US Patent 7806886 Apparatus and method for controlling insulin infusion with state variable feedback
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US Patent 7819843 External infusion device with remote programming, bolus estimator and/or vibration alarm capabilities
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US Patent 7850641 Safety limits for closed-loop infusion pump control
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US Patent 7860544 Analyte monitoring device and methods of use
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US Patent 7879026 Controlled adjustment of medicine dispensation from an infusion pump device
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US Patent 7890295 Real time self-adjusting calibration algorithm
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US Patent 7899545 Methods and systems for semi-automatic adjustment of medical monitoring and treatment
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US Patent 7901394 Physiological monitoring device for controlling a medication infusion device
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US Patent 7912684 Diabetes care management system
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US Patent 7920998 Diabetes care management system
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US Patent 7925321 System and methods for processing analyte sensor data
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US Patent 7937255 Diabetes care management system
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US Patent 7941200 System and method for determining drug administration information
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US Patent 7959569 System and methods for processing analyte sensor data
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US Patent 7963917 System and method for continuous non-invasive glucose monitoring
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US Patent 7988630 Method and system for implantable glucose monitoring and control of a glycemic state of a subject
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US Patent 8062249 Overnight closed-loop insulin delivery with model predictive control and glucose measurement error model
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US Patent 8088098 Tailored basal insulin delivery system and method
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US Patent 8105268 Safety limits for closed-loop infusion pump control
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US Patent 8109921 Operating a portable medical device
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US Patent 8112375 Wavelength selection and outlier detection in reduced rank linear models
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US Patent 8114023 Analyte sensing and response system
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US Patent 8140312 Method and system for determining analyte levels
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US Patent 8152789 System and method for providing closed loop infusion formulation delivery
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US Patent 8162829 Analyte monitoring device and methods of use
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US Patent 8177716 Analyte monitoring device and methods of use
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US Patent 8192395 System for providing blood glucose measurements to an infusion device
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US Patent 8208984 Correction factor testing using frequent blood glucose input
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US Patent 8226556 Algorithm sensor augmented bolus estimator for semi-closed loop infusion system
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US Patent 8229872 Modeling and control for highly variable and nonlinear systems
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US Patent 8257300 Safety features for integrated insulin delivery system
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US Patent 8273052 Fully automated control system for type 1 diabetes
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US Patent 8287487 Infusion pump system and methods
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US Patent 8290562 System and methods for processing analyte sensor data
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US Patent 8318154 Super fast-acting insulin compositions
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US Patent 8346399 Programmable insulin pump
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US Patent 8348886 Apparatus and method for controlling insulin infusion with state variable feedback
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US Patent 8348923 Apparatus and method for controlling insulin infusion with state variable feedback
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US Patent 8377031 Closed loop control system with safety parameters and methods
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US Patent 8398616 Safety layer for integrated insulin delivery system
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US Patent 8409131 Analyte monitoring device and methods of use
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US Patent 8414523 Infusion pump with add-on modules
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US Patent 8449524 Fluid component analysis systems and methods for glucose monitoring and control
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US Patent 8460231 Integrated delivery device for continuous glucose sensor
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US Patent 8467972 Closed loop blood glucose control algorithm analysis
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US Patent 8478557 Method and apparatus for providing analyte monitoring system calibration accuracy
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US Patent 8480580 Analyte monitoring device and methods of use
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US Patent 8480649 Method for selecting bolus doses and bolus delivery patterns in a drug delivery device
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US Patent 8504179 Programmable medical infusion pump
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US Patent 8527208 Prandial blood glucose excursion optimization method via computation of time-varying optimal insulin profiles and system thereof
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US Patent 8532933 Insulin optimization systems and testing methods with adjusted exit criterion accounting for system noise associated with biomarkers
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US Patent 8548544 System, method and article for controlling the dispensing of insulin
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US Patent 8560082 Computerized determination of insulin pump therapy parameters using real time and retrospective data processing
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US Patent 8562587 CGM-based prevention of hypoglycemia via hypoglycemia risk assessment and smooth reduction of insulin delivery
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US Patent 8579854 Integrated insulin delivery system having delivery safety features
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US Patent 8585591 Method and system for providing basal profile modification in analyte monitoring and management systems
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US Patent 8585593 Method, system, and computer program product for the detection of physical activity by changes in heart rate, assessment of fast changing metabolic states, and applications of closed and open control loop in diabetes
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US Patent 8585637 Method of overnight closed-loop insulin delivery with model predictive control and glucose measurement error model
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US Patent 8597274 Usability features for integrated insulin delivery system
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US Patent 8615366 Handheld diabetes management device with bolus calculator
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US Patent 8622988 Variable rate closed loop control and methods
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US Patent 8647321 Method of monitoring safety in medication delivery for diabetes management
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US Patent 8657807 Insulin pump having a suspension bolus
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US Patent 8660800 Multi-treatment planning apparatus and method
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US Patent 8688386 Analyte testing method and device for calculating basal insulin therapy
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US Patent 8690820 Automatic insulin pumps using recursive multivariable models and adaptive control algorithms
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US Patent 8690856 Insulin pump having missed meal bolus alarm
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US Patent 8718943 Method and device for utilizing analyte levels to assist in the treatment of diabetes
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US Patent 8718965 Method and apparatus for providing analyte monitoring system calibration accuracy
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US Patent 8732188 Method and system for providing contextual based medication dosage determination
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US Patent 8734422 Closed loop control with improved alarm functions
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US Patent 8734428 Insulin pump having selectable insulin absorption models
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US Patent 8744545 Analyte monitoring device and methods of use
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US Patent 8753316 Insulin pump for determining carbohydrate consumption
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US Patent 8756043 Blood glucose meter and computer-implemented method for improving glucose management through modeling of circadian profiles
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US Patent 8762070 Systems, devices and methods to deliver biological factors or drugs to a subject
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US Patent 8771222 Apparatus and method for controlling insulin infusion with state variable feedback
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US Patent 8777896 System and method for providing closed loop infusion formulation delivery
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US Patent 8777924 Apparatus and method for controlling insulin infusion with state variable feedback
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US Patent 8784369 System and method for providing closed loop infusion formulation delivery
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US Patent 8784370 Safety limits for closed-loop infusion pump control
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US Patent 8788044 Systems and methods for tissue stimulation in medical treatment
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US Patent 8795224 System and method for providing closed loop infusion formulation delivery
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US Patent 8795252 Robust closed loop control and methods
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US Patent 8821433 Insulin pump having basal rate testing features
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US Patent 8823528 Infusion pump having an alarm signal
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US Patent 8825166 Multiple-symptom medical treatment with roving-based neurostimulation
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US Patent 8831735 Methods and systems for semi-automatic adjustment of medical monitoring and treatment
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US Patent 8840553 Analyte monitoring device and methods of use
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US Patent 8840582 Infusion pump with activity monitoring
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US Patent 8876755 Closed loop control system interface and methods
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US Patent 8876803 System for monitoring safety in medication delivery for diabetes management
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US Patent 8924160 Health-monitoring device
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US Patent 8924161 System for use in the treatment of diabetes
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US Patent 8926585 Integrated delivery device for continuous glucose sensor
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US Patent 8930203 Multi-function analyte test device and methods therefor
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US Patent 8932216 Method and system for providing data management in integrated analyte monitoring and infusion system
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US Patent 8936573 Infusion pump having missed bolus alarm
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US Patent 8945094 Apparatus and method for medication delivery using single input-single output (SISO) model predictive control
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US Patent 8954373 Monitoring device for management of insulin delivery
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US Patent 8961416 System for monitoring physiological characteristics
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US Patent 8961465 Insulin pump having a food database
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US Patent 8965509 Methods and systems for semi-automatic adjustment of medical monitoring and treatment
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US Patent 8974439 Infusion pump system and methods
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US Patent 8977504 Substance monitoring and control in human or animal bodies
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US Patent 8998878 Insulin pump having correction factors
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US Patent 9017311 Integrated diabetes management system using safety layer
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US Patent 9037254 Methods and systems for semi-automatic adjustment of medical monitoring and treatment
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US Patent 9056167 Method and device for drug delivery
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US Patent 9056168 System, method and article for controlling the dispensing of insulin
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US Patent 9066694 Analyte monitoring device and methods of use
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US Patent 9089292 Calibration of glucose monitoring sensor and/or insulin delivery system
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US Patent 9089713 Methods and systems for semi-automatic adjustment of medical monitoring and treatment
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US Patent 9114210 Infusion pump system and methods
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US Patent 9119528 Systems and methods for providing sensitive and specific alarms
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US Patent 9192750 Method and device for controlling drug pharmacokinetics
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US Patent 9199031 Maintaining glycemic control during exercise
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US Patent 9220456 Systems, methods and devices for achieving glycemic balance
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US Patent 9227014 Kalman filter based on-off switch for insulin pump
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US Patent 9244077 Method system and device for assessing insulin sensitivity
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US Patent 9254362 Activity sensing techniques for an infusion pump system
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US Patent 9283323 Insulin pump
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US Patent 9302045 Fluid component analysis system and method for glucose monitoring and control
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US Patent 9320471 Algorithm sensor augmented bolus estimator for semi-closed loop infusion system
0
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US Patent 9323898 Method and system for providing basal profile modification in analyte monitoring and management systems
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US Patent 9330237 Pattern recognition and filtering in a therapy management system
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US Patent 9333298 Apparatus and method for automatically supplying insulin based on amount of exercise
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US Patent 9364609 Insulin on board compensation for a closed-loop insulin infusion system
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US Patent 9364679 System for providing therapy to a patient
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US Patent 9398869 Method, system, and computer program product for improving the accuracy of glucose sensors using insulin delivery observation in diabetes
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US Patent 9399096 Automatic closed-loop control adjustments and infusion systems incorporating same
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US Patent 9402953 Integrated closed-loop medication delivery with error model and safety check
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US Patent 9420968 Systems and methods for replacing signal artifacts in a glucose sensor data stream
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US Patent 9440025 Apparatus and method for controlling insulin infusion with state variable feedback
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US Patent 9445757 Glycemic health metric determination and application
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US Patent 9457145 Method and device for improving glycemic control
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US Patent 9474855 Method and system for controlling a tuning factor due to sensor replacement for closed-loop controller in an artificial pancreas
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US Patent 9480796 System and method for providing closed loop infusion formulation delivery
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US Patent 9483619 Means and method for improved glycemic control for diabetic patients
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US Patent 9486171 Predictive calibration
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US Patent 9486578 Method and system for tuning a closed-loop controller for an artificial pancreas
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US Patent 9507917 Monitoring device for management of insulin delivery
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US Patent 9510782 Systems and methods for replacing signal artifacts in a glucose sensor data stream
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US Patent 9517306 Method and system for closed-loop control of an artificial pancreas
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US Patent 9526834 Safeguarding measures for a closed-loop insulin infusion system
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US Patent 9572934 Robust closed loop control and methods
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US Patent 9579456 Methods for reducing false hypoglycemia alarm occurrence
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US Patent 9597451 Insulin delivery safety
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US Patent 9610046 Closed loop control with improved alarm functions
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US Patent 9619625 System for optimizing a patient's drug dosage regimen over time
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US Patent 9623179 Safeguarding techniques for a closed-loop insulin infusion system
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US Patent 9629957 Ambulatory insulin infusion system with bolus administration delay
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US Patent 9636461 System for optimizing a drug dosage regimen over time
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US Patent 9649439 Systems and methods for facilitating patient-based adjustment of drug infusion
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US Patent 9662445 Regulating entry into a closed-loop operating mode of an insulin infusion system
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US Patent 9669160 Temporary suspension for closed-loop medicament therapy
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US Patent 9669162 Method and system for providing basal profile modification in analyte monitoring and management systems
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US Patent 9687194 Closed-loop glucose and/or insulin control system
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US Patent 9693700 ECG rhythym advisory method
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US Patent 9694133 System, method and article for controlling the dispensing of insulin
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US Patent 9700708 Maintaining multiple defined physiological zones using model predictive control
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US Patent 9717848 Data derived pre-bolus delivery
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US Patent 9724470 System for monitoring and delivering medication to a patient and method of using the same to minimize the risks associated with automated therapy
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US Patent 9750438 CGM-based prevention of hypoglycemia via hypoglycemia risk assessment and smooth reduction of insulin delivery
0
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US Patent 9757510 Method and system to handle manual boluses or meal events for closed-loop controllers
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US Patent 9782540 Safety limits for closed-loop infusion pump control
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US Patent 9795737 Method and system for closed-loop control of an artificial pancreas
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US Patent 9808577 Device, system and method for facilitating syringe based drug delivery and management thereof
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US Patent 9833177 Insulin pump based expert system
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US Patent 9833191 Computer-based diabetes management
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US Patent 9833570 Blood glucose control system
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US Patent 9833571 System for monitoring safety in medication delivery for diabetes management
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US Patent 9844627 Infusion pump system and methods
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US Patent 9848774 System and methods for improved diabetes data management and use employing wireless connectivity between patients and healthcare providers and repository of diabetes management information
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US Patent 9849239 Generation and application of an insulin limit for a closed-loop operating mode of an insulin infusion system
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US Patent 9861310 Algorithms for diabetes exercise therapy
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US Patent 9861747 Method and system for management of diabetes with a glucose monitor and infusion pump to provide feedback on bolus dosing
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US Patent 9861748 User-configurable closed-loop notifications and infusion systems incorporating same
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US Patent 9872890 Determining insulin dosing schedules and carbohydrate-to-insulin ratios in diabetic patients
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US Patent 9878096 Generation of target glucose values for a closed-loop operating mode of an insulin infusion system
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US Patent 9878097 Operating an infusion pump system
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US Patent 9886556 Diabetes management therapy advisor
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US Patent 9889250 Infusion pump with temperature monitoring
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US Patent 9907515 Health monitoring system
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US Patent 9907909 Method and system for a hybrid control-to-target and control-to-range model predictive control of an artificial pancreas
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US Patent 9913599 Software applications residing on handheld analyte determining devices
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US Patent 9918635 Systems and methods for optimizing insulin dosage
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US Patent 9919105 Devices, systems and methods for quantifying bolus doses according to user parameters
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US Patent 9936910 Method and apparatus for providing analyte monitoring and therapy management system accuracy
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US Patent 9943644 Closed loop control with reference measurement and methods thereof
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US Patent 9943645 Methods for operating mode transitions and related infusion devices and systems
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US Patent 9965596 Means and method for improved glycemic control for diabetic patients
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US Patent 9984773 Moving-horizon state-initializer for control applications
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US Patent 9990581 Insulin dosage assessment and recommendation system
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US Patent 9999728 Regulating entry into a closed-loop operating mode of an insulin infusion system
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US Patent 10007765 Adaptive signal processing for infusion devices and related methods and systems
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US Patent 10010273 Multi-function analyte monitor device and methods of use
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US Patent 10016561 Clinical variable determination
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US Patent 10022498 System for monitoring and delivering medication to a patient and method of using the same to minimize the risks associated with automated therapy
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US Patent 10046113 Systems and methods for determining insulin therapy for a patient
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US Patent 10052049 Infusion pump with blood glucose alert delay
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US Patent 10080529 System for monitoring physiological characteristics
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US Patent 10130765 Integrated insulin delivery system having safety features to prevent hypoglycemia
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US Patent 6923763 Method and apparatus for predicting the risk of hypoglycemia
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US Patent 7022072 System for monitoring physiological characteristics
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US Patent 7025743 External infusion device with remote programming, bolus estimator and/or vibration alarm capabilities
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US Patent 7060059 System and method for initiating and maintaining continuous, long-term control of a concentration of a substance in a patient using a feedback or model-based controller coupled to a single-needle or multi-needle intradermal (ID) delivery device
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Patent Primary Examiner
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Nathan R Price
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CPC Code
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A61M 2202/0486
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A61B 5/7275
0
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A61M 5/1723
0

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