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US Patent 11866451 Salts and crystalline forms of a PD-1/PD-L1 inhibitor

Patent 11866451 was granted and assigned to Incyte on January, 2024 by the United States Patent and Trademark Office.

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Is a
Patent
Patent
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Patent attributes

Patent Applicant
Incyte
Incyte
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Current Assignee
Incyte
Incyte
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
118664510
Patent Inventor Names
Shili Chen0
Qun Li0
Jiacheng Zhou0
Yi Li0
Zhongjiang Jia0
Timothy Martin0
Bo Shen0
Naijing Su0
Date of Patent
January 9, 2024
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Patent Application Number
170943960
Date Filed
November 10, 2020
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Patent Citations
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US Patent 7691870 Benzimidazole carboxamides as raf kinase inhibitors
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US Patent 7851489 Pyridinone compounds
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US Patent 7943743 Human monoclonal antibodies to programmed death ligand 1 (PD-L1)
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US Patent 8008449 Human monoclonal antibodies to programmed death 1 (PD-1) and methods for treating cancer using anti-PD-1 antibodies alone or in combination with other immunotherapeutics
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US Patent 8163743 4-carboxamide indazole derivatives useful as inhibitors of PI3-kinases
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US Patent 6867200 (Hetero)aryl-bicyclic heteroaryl derivatives, their preparation and their use as protease inhibitors
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US Patent 7320989 Pyridine, pyrimidine, quinoline, quinazoline, and naphthalene urotensin-II receptor antagonists
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US Patent 7417065 Immunosuppressant compounds and compositions
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...
Patent Citations Received
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US Patent 12084443 Process of preparing a PD-1/PD-L1 inhibitor
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Patent Primary Examiner
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Sahar Javanmard
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CPC Code
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C07C 2602/42
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C07C 211/56
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C07B 2200/13
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C07C 61/135
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C07D 519/00
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Patent abstract

This application relates to solid forms and salt forms of the PD-1/PD-L1 inhibitor 4,4′-(((((2,2′-dichloro-[1,1′-biphenyl]-3,3′-diyl)bis(azanediyl))bis(carbonyl))bis(1-methyl-1,4,6,7-tetrahydro-5H-imidazo[4,5-c]pyridine-2,5-diyl))bis(ethane-2,1-diyl))bis(bicyclo[2.2.1]heptane-1-carboxylic acid), including processes of preparation thereof, where the solid forms and salt forms are useful in the treatment of various diseases including infectious diseases and cancer.

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