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US Patent 11858996 Anti-ICOS antibodies

Patent 11858996 was granted and assigned to Kymab on January, 2024 by the United States Patent and Trademark Office.

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Is a
Patent
Patent
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Patent attributes

Patent Applicant
Kymab
Kymab
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Current Assignee
Kymab
Kymab
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
118589960
Patent Inventor Names
Miha Kosmac0
Ian Kirby0
Robert Rowlands0
Nahida Parveen0
Volker Germaschewski0
Stephen John Arkinstall0
Richard Charles Alfred Sainson0
Jamie Iain Campbell0
...
Date of Patent
January 2, 2024
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Patent Application Number
163239800
Date Filed
August 9, 2017
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Patent Citations
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US Patent 7196175 Antibodies to JTT-1 protein and cells secreting such antibodies
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US Patent 7030225 Antibodies to JTT-1 protein, cells secreting such antibodies, and methods of making such antibodies
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US Patent 7045615 Nucleic acids encoding JTT-1 protein
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US Patent 7125551 Methods for treatment of asthmatic disorders using a monoclonal antibody to 8F4 polypeptide
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US Patent 7132099 Methods of modulating T lymphocyte costimulation with an antibody to an 8F4 polypeptide
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US Patent 7166283 Methods of treating an inflammatory disorder and prohibiting proliferation, cytokine production, and signal transduction with antibody against costimulatory signal transduction molecule AILIM
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US Patent 8318905 Antibodies for depletion of ICOS-positive cells in vivo
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US Patent 8389690 Antibodies to JTT-1 protein and cells secreting such antibodies
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...
Patent Primary Examiner
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Ilia I Ouspenski
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Patent abstract

Antibodies that bind ICOS (Inducible T cell Co-Stimulator). Therapeutic use of anti-ICOS antibodies for modulating the ratio between regulatory T cells and effector T cells, to stimulate the immune system of patients, including use in treating cancers. Methods of producing anti-ICOS antibodies, including species cross-reactive antibodies, using transgenic knock-out mice.

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