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US Patent 11857603 PTH compounds with low peak-to-trough ratios

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Is a

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Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Mathias Krusch0

Joachim Zettler0

Felix Cleemann0

David Brian Karpf0

Kennett Sprogøe0

Lars Holten-Andersen0

Thomas Wegge0

Guillaume Maitro0

Date of Patent

January 2, 2024

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Patent Application Number

180537010

Date Filed

November 8, 2022

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Patent Citations

US Patent 8101729 Pegylated amino acid derivatives and the process to synthesize the same

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US Patent 8618124 Heterobifunctional polymeric bioconjugates

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US Patent 8754190 Controlled release from macromolecular conjugates

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US Patent 8865220 Method for controlled release of parathyroid hormone from encapsulated poly(lactic-glycolic)acid microspheres

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US Patent 8906847 Prodrug comprising a drug linker conjugate

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US Patent 10980860 Diagnosis, prevention and treatment of diseases of the joint

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US Patent 8946405 Controlled release from solid supports

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US Patent 11590207 Dosage regimen for a controlled-release PTH compound

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Patent Primary Examiner

Christina Bradley

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Patent abstract

The present invention relates to a pharmaceutical composition comprising a PTH compound, wherein after subcutaneous administration the pharmacokinetic profile of the PTH compound exhibits a peak to trough ratio of less than 4 within one injection interval.

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