Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Aaron Ring0
Tom Boone0
Date of Patent
December 26, 2023
0Patent Application Number
180608160
Date Filed
December 1, 2022
0Patent Citations Received
Patent Primary Examiner
CPC Code
Patent abstract
The present disclosure provides compositions and methods comprising stabilized IL-18 polypeptides for use in therapeutic and non-therapeutic applications. In some cases, the stabilized IL-18 proteins provide IL-18 signaling activity even in the presence of an inhibitory molecule such as IL-18BP. Also provide are methods of administration and methods for making active polypeptides.
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