A removable cartridge cleaner assembly is provided that allows for easier replacement of the belt cleaner blades from under a conveyor belt. In one aspect the assembly includes a cartridge assembly configured for connection with at least one belt cleaner blade assembly and a support assembly configured to support the cartridge assembly across a transverse width of the conveyor belt. A releasable connection between the cartridge assembly and the support assembly is configured to be sheltered from dust and debris. The releasable connection may be disposed within a chamber formed by the engaging portions of the cartridge and support assemblies. The releasable connection can be released by removing a longitudinally oriented rod member that extends along a length of the cartridge and support assemblies. The support assembly may include a secondary cartridge support for easing installation and removal of the cartridge assembly.