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US Patent 11835496 Sample metering and injection for liquid chromatography

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Is a
Patent
Patent
0

Patent attributes

Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
118354960
Patent Inventor Names
Joshua A. Burnett0
Rose Solow0
David A. Simpson0
Date of Patent
December 5, 2023
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Patent Application Number
171262360
Date Filed
December 18, 2020
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Patent Citations
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US Patent 7288228 Sample injection system
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US Patent 9435773 Sample injector with metering device balancing pressure differences in an intermediate valve state
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US Patent 9624923 Control arrangement for controlling a piston pump unit for liquid chromatography
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US Patent 9664653 Method for feeding a sample into an analysis branch of a liquid chromatography system
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US Patent 9841406 Switching valve for flow type analysis apparatus
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US Patent 10371671 Branching off fluidic sample with low influence on source flow path
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US Patent 10473631 Sampler for liquid chromatography
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US Patent 10473632 Metering device with defined enabled flow direction
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...
Patent Primary Examiner
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David L Singer
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CPC Code
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G01N 30/24
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G01N 30/36
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G01N 2030/201
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G01N 2030/202
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G01N 30/20
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G01N 2030/027
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Patent abstract

A method and a fluidic network for acquiring and injecting a chromatographic sample into a chromatography system flow include a metering pump module, a sample needle, a needle seal and an injection valve. The metering pump module includes a metering pump and a pressure transducer in serial fluidic communication. When the injection valve is in a first valve state, the injection valve is configured to fluidically terminate ports of the metering pump module. When the injection valve is in a second valve state, the injection valve is configured to fluidically couple a fluidic path that includes the metering pump module and sample needle into the system flow of a chromatography system without resulting in a substantial change in the pressure of the system flow.

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