US Patent 11827639 TDO2 and IDO1 inhibitors
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US Patent 11827639 TDO2 and IDO1 inhibitors
Article
Patent abstract
Presently provided are inhibitors of TD02 and IDO1 and pharmaceutical compositions thereof, useful for modulating an activity of tryptophan 2,3 dioxygenase and indoleamine 2,3-dioxygenase 1; treating immunosuppression; treating a medical conditions that benefit from the inhibition of tryptophan degradation; enhancing the effectiveness of an anti-cancer treatment comprising administering an anti-cancer agent; and treating tumor-specific immunosuppression associated with cancer.
Infobox
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Patent Number
Patent Inventor Names
Brendan Parr0
Firoz Jaipuri0
Guoshen Wu0
Hima Potturi0
Lewis Gazzard0
Powai Yuen0
Richard Pastor0
Sanjeev Kumar0
Wendy Liu0
Xingyu Lin0
Yanyan Chu0
Zhonghua Pei0
Date of Patent
November 28, 2023
0Patent Application Number
166261910
Date Filed
June 28, 2018
0Patent Citations
Patent Primary Examiner
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