An orthodontic post and pin system for secure attachment of a dental appliance to an alignment wire, which also facilitates quick and easy removal and replacement. The system described herein uses a “twist-lock” dental post that is rotated onto, and counter-rotated off of, an alignment wire. The dental post includes structural elements to facilitate the twist-lock functionality, as well as structures for accepting a fastener to secure the alignment wire in place and inhibit unintentional or undesired dislodging.