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US Patent 11779656 Gene therapy for treating hemophilia A

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Is a

Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

Patent Inventor Names

James M. Wilson

Lili Wang

Jenny Agnes Sidrane

Date of Patent

October 10, 2023

Patent Application Number

16093798

Date Filed

April 13, 2017

Patent Citations

US Patent 7341871 Nucleotide sequences for gene regulation and methods of use thereof

US Patent 7351577 Adeno-associated vector compositions for expression of Factor VIII

US Patent 7351813 Liver-specific gene expression cassettes, and methods of use

US Patent 7572619 Recombinant blood clotting factors

US Patent 7635763 Nucleic acid and amino acid sequences encoding high-level expressor factor VIII polypeptides and methods of use

US Patent 7847088 Classification and diagnosis of the molecular basis of cholestasis

US Patent 7855274 Recombinant factor VIII having increased specific activity

US Patent 7943374 Super-size adeno-associated viral vector harboring a recombinant genome larger than 5.7 kb

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Patent Primary Examiner

Patent abstract

Compositions and regimens useful in treating hemophilia A are provided. The compositions include recombinant adeno-associated virus (rAAV) with a transthyretin enhancer and promoter driving expression of a human Factor VIII.

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