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US Patent 11771747 Multiepitope vaccine cassettes

Patent 11771747 was granted and assigned to Gritstone Bio on October, 2023 by the United States Patent and Trademark Office.

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Contents

Is a
Patent
Patent

Patent attributes

Patent Applicant
Gritstone Bio
Gritstone Bio
Current Assignee
Gritstone Bio
Gritstone Bio
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
11771747
Patent Inventor Names
Ciaran Daniel Scallan
Leonid Gitlin
Roman Yelensky
James Xin Sun
Monica Lane
Karin Jooss
Amy Rachel Rappaport
Christine Denise Palmer
Date of Patent
October 3, 2023
Patent Application Number
17727610
Date Filed
April 22, 2022
Patent Citations
‌
US Patent 7468181 Means and methods for the production of adenovirus vectors
‌
US Patent 7531180 Chimeric alphavirus replicon particles
‌
US Patent 7541038 Fusogenic, self-propagating blebs as immunogenic compositions
‌
US Patent 7557200 Superior molecular vaccine based on self-replicating RNA, suicidal DNA or naked DNA vector, that links antigen with polypeptide that promotes antigen presentation
‌
US Patent 7572453 Chimeric alphavirus replicon particles
‌
US Patent 7572628 Eukaryotic layered vector initiation systems
‌
US Patent 7605235 Anti-tissue factor antibodies and compositions
‌
US Patent 7732129 Method for the production and purification of adenoviral vectors
...
Patent Primary Examiner
‌
Kevin K Hill
CPC Code
‌
C12N 15/86
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A61K 39/0011
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A61K 2039/5256
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A61K 39/00
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A61K 39/005
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A61K 2039/53
Patent abstract

Disclosed herein are compositions that include antigen-encoding nucleic acid sequences having multiple iterations of KRAS neoepitope-encoding sequences and/or lacking immunodominant epitopes. Also disclosed are nucleotides, cells, and methods associated with the compositions including their use as vaccines.

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