A medicinal pair of underwear is configured to reduce pressure exerted against a women's body to reduce or remove pain caused by underwear due to nerve pain in the abdomen, thigh, genital area, or hip crease. The underwear includes a front waistband that is connected to a front portion of the underwear via stitching, and a rear waistband that is connected to the rear waistband via stitching. The stitching for the front and rear waistbands do not engage, that is, there is a gap present between the stitching for the rear waistband and the front waistband to reduce the amount of pressure exerted while the medicinal underwear is worn. The collective structural features provide a loose-fitting medicinal pair of underwear that, when worn, stays in place and can be utilized by women who are experiencing nerve pain around the genital and thigh areas.