US Patent 11753632 Highly potent acid alpha-glucosidase with enhanced carbohydrates
Patent 11753632 was granted and assigned to Amicus Therapeutics on September, 2023 by the United States Patent and Trademark Office.
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US Patent 11753632 Highly potent acid alpha-glucosidase with enhanced carbohydrates
Article
Recombinant human alpha glucosidase (rhGAA) composition derived from CHO cells that contains a more optimized glycan composition consisting of a higher amount of rhGAA containing N-glycans carrying mannose-6-phosphate (M6P) or bis-M6P than conventional rhGAAs, along with low amount of non-phosphorylated high mannose glycans, and low amount of terminal galactose on complex oligosaccharides. Compositions containing the rhGAA, and methods of use are described.
Infobox
Is a
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
11753632
Patent Inventor Names
Hung V. Do
Russell Gotschall
Date of Patent
September 12, 2023
Patent Application Number
17249175
Date Filed
February 23, 2021
Patent Citations
Patent Primary Examiner
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