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US Patent 11707456 Processes for preparing arimoclomol citrate and intermediates thereof

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 US Patent 11707456 Processes for preparing arimoclomol citrate and intermediates thereof

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The present disclosure relates to a process for preparing arimoclomol, arimoclomol citrate and key intermediates, such as ORZY-01, thereof. The disclosure further relates to a process for preparing high purity arimoclomol citrate and methods of using the same.

Infobox
Is a
Patent
Patent
0
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
117074560
Date of Patent
July 25, 2023
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Patent Application Number
176919890
Date Filed
March 10, 2022
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Patent Citations
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US Patent 7125843 Glycoconjugates including more than one peptide
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US Patent 7126002 Pyridine-1-oxide derivative, and process for its transformation into pharmaceutically effective compounds
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US Patent 7148239 Method of enhancing cellular production of molecular chaperon, hydroxylamine derivatives useful for enhancing the chaperon production and the preparation thereof
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US Patent 7326574 Compositions and methods for detecting stress-inducible proteins
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US Patent 7361655 Pharmaceutically effective compounds
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US Patent 7384936 Carboxamidine derivatives and their use in the treatment of vascular diseases
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US Patent 7396681 Application of Hsp70 proteins
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US Patent 7517948 Hsp70 peptide stimulating natural killer (NK) cell activity and uses thereof
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US Patent 7550457 Pharmaceutically effective compounds
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US Patent 7691849 Carboxamidine derivatives and their use in the treatment of vascular diseases
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US Patent 7745465 Method of enhancing cellular production of molecular chaperone, hydroxylamine derivatives useful for enhancing the chaperone production and the preparation thereof
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US Patent 7750050 Chaperone-based therapy for Niemann-Pick disease
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US Patent 8540985 Use of Hsp70 as a regulator of enzymatic activity
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US Patent 8962604 Use of a hydroximic acid halide derivative in the treatment of neurodegenerative diseases
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US Patent 9289472 Use of HSP70 as a regulator of enzymatic activity
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US Patent 9662375 Methods for increasing intracellular activity of Hsp70
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US Patent 9884058 Use of Hsp70 as a regulator of enzymatic activity
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US Patent 10532085 Methods for increasing intracellular activity of Hsp70
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US Patent 10543204 Use of Hsp70 as a regulator of enzymatic activity
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US Patent 11045460 Use of Hsp70 as a regulator of enzymatic activity
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US Patent 11253505 Arimoclomol for treating glucocerebrosidase associated disorders
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US Patent 11304941 Use of HSP70 as a regulator of enzymatic activity
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Patent Primary Examiner
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Mark V Stevens
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CPC Code
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C07D 213/89
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C07D 401/12
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A61K 31/00
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A61K 31/4545
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