US Patent 11701021 Lesion assessment using peak-to-peak impedance amplitude measurement

A method and system for lesion formation assessment in tissue that has undergone an ablation procedure. In one embodiment, a method of assessing lesion formation comprises: recording a baseline impedance measurement from an area of tissue with a medical device; ablating the area of tissue with the medical device; recording a post-treatment impedance measurement from the area of tissue with the medical device; identifying at least one amplitude characteristic of the baseline impedance measurement and identifying at least one amplitude characteristic of the post-treatment impedance measurement; comparing the at least one amplitude characteristic of the baseline impedance measurement and the at least one amplitude characteristic of the post-treatment impedance measurement; generating an indication of efficacy based on the comparison, the indication of efficacy being one of sufficient lesion formation and insufficient lesion formation; and re-ablating the area of tissue if the indication of efficacy is insufficient lesion formation.