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US Patent 11691938 Process for preparing 2,6-dialkylphenylacetic acids

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United States Patent and Trademark Office

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Patent Number

Date of Patent

July 4, 2023

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Patent Application Number

170459390

Date Filed

April 3, 2019

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Patent Citations

US Patent 7897543 Spiroketal-substituted cyclic ketoenols

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US Patent 8507688 Process for preparing aryl- and heteroarylacetic acid derivatives

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The invention relates to a multi-stage process for preparing 2,6-dialkylphenylacetic acids of the general formula (I) by reacting 2,6-dialkylbromobenzenes with (1) magnesium, (2) a formamide, (3) an acid, (4) hydrogenation of the benzaldehyde obtained, (5) activation of the benzyl alcohol obtained, (6) cyanation of the activated benzyl alcohol and (7) hydrolysis of the nitrile obtained.

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