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US Patent 11690918 Pyrrolobenzodiazepine-anti-CD22 antibody conjugates

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Date of Patent

July 4, 2023

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Patent Application Number

168831390

Date Filed

May 26, 2020

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Patent Citations

US Patent 7407951 Pyrrolobenzodiazepines

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US Patent 7429658 Synthesis of protected pyrrolobenzodiazepines

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US Patent 7511032 Pyrrolobenzodiazepine derivatives, compositions comprising the same and methods related thereto

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US Patent 7521541 Cysteine engineered antibodies and conjugates

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US Patent 7528126 Pyrrolobenzodiazepines

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US Patent 7557099 Pyrrolobenzodiazepines as key intermediates in the synthesis of dimeric cytotoxic pyrrolobenzodiazepines

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US Patent 7612062 Pyrrolobenzodiazepines

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US Patent 7704924 Library of compounds comprising pyrrolobenzodiazepine moieties

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Patent Primary Examiner

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The disclosure provides conjugates of an isolated humanized anti-CD22 antibody and PBD dimers.

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