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US Patent 11667965 Sequence assembly

Patent 11667965 was granted and assigned to InVitae on June, 2023 by the United States Patent and Trademark Office.

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US Patent 12024285 Modular mobility system including thrusters movably connected to a support structure
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 US Patent 11667965 Sequence assembly

Article

The invention relates to assembly of sequence reads. The invention provides a method for identifying a mutation in a nucleic acid involving sequencing nucleic acid to generate a plurality of sequence reads. Reads are assembled to form a contig, which is aligned to a reference. Individual reads are aligned to the contig. Mutations are identified based on the alignments to the reference and to the contig.

Infobox
Is a
Patent
Patent
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Patent Applicant
InVitae
InVitae
0
Current Assignee
InVitae
InVitae
0
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
116679650
Date of Patent
June 6, 2023
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Patent Application Number
167905190
Date Filed
February 13, 2020
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Patent Citations
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US Patent 7115400 Methods of nucleic acid amplification and sequencing
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US Patent 7169560 Short cycle methods for sequencing polynucleotides
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US Patent 7211390 Method of sequencing a nucleic acid
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US Patent 7232656 Arrayed biomolecules and their use in sequencing
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US Patent 7244559 Method of sequencing a nucleic acid
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US Patent RE39793 Compositions for sorting polynucleotides
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US Patent 7264929 Method of sequencing a nucleic acid
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US Patent 7282337 Methods for increasing accuracy of nucleic acid sequencing
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US Patent 7320860 Nucleic acid amplification method
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US Patent 7351528 Probing of specific nucleic acids
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US Patent 7393665 Methods and compositions for tagging and identifying polynucleotides
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US Patent 7510829 Multiplex PCR
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US Patent 7537889 Assay for quantitation of human DNA using
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US Patent 7544473 Nucleic acid analysis using sequence tokens
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US Patent 7582431 Enhanced sequencing by hybridization using pools of probes
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US Patent 7642056 Method and kit for detecting a target protein using a DNA aptamer
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US Patent 7666593 Single molecule sequencing of captured nucleic acids
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US Patent 7700323 Method for detecting and amplifying target DNA
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US Patent 7774962 Removable and reusable tags for identifying bottles, cans, and the like
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US Patent 7776616 Apparatuses and methods for isolating nucleic acid
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US Patent RE41780 Chemical amplification based on fluid partitioning in an immiscible liquid
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US Patent 7809509 Comparative mapping and assembly of nucleic acid sequences
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US Patent 7835871 Nucleic acid sequencing system and method
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US Patent 7862999 Multiplex targeted amplification using flap nuclease
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US Patent 7865534 System, method and apparatus for assembling and mining life science data
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US Patent 7957913 Evaluating genetic disorders
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US Patent 7960120 Method for pair-wise sequencing a plurality of double stranded target polynucleotides
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US Patent 7993880 Precircle probe nucleic acid amplification methods
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US Patent 8024128 System and method for improving clinical decisions by aggregating, validating and analysing genetic and phenotypic data
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US Patent 8165821 System and methods for indel identification using short read sequencing
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US Patent 8209130 Sequence assembly
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US Patent 8462161 System and method for fast component enumeration in graphs with implicit edges
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US Patent 8474228 Packaging systems and methods for transporting vials
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US Patent 8496166 System for associating RFID tag with UPC code, and validating associative encoding of same
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US Patent 8529744 Enrichment of nucleic acid targets
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US Patent 8738300 Sequence assembly
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US Patent 8778609 Methods for analyzing nucleic acids
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US Patent 8812422 Variant database
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US Patent 8829171 Linking sequence reads using paired code tags
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US Patent 8847799 Methods and systems for storing sequence read data
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US Patent 8976049 Methods and systems for storing sequence read data
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US Patent 9045801 Biomarkers for non-hodgkin lymphomas and uses thereof
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US Patent 9074244 Array-based translocation and rearrangement assays
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US Patent 9092401 System and methods for detecting genetic variation
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US Patent 9115387 Methods for analyzing nucleic acids
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US Patent 9292527 Methods and systems for storing sequence read data
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US Patent 9535920 Methods and systems for storing sequence read data
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US Patent 10066259 Screening for structural variants
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US Patent 10202637 Methods for analyzing nucleic acid
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US Patent 10227635 Capture reactions
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US Patent 10235494 Strategies for high throughput identification and detection of polymorphisms
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US Patent 10604799 Sequence assembly
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US Patent 10683533 Capture reactions
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Patent Primary Examiner
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John S. Brusca
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