A vise having a modular construction that allows for ease of manufacture, assembly, and changeover or replacement of wear items, such as gripping surfaces of jaws of the vise. The modular construction also provides for reduced weight of the vise compared to conventional cast type vises. The vise also incorporates quick adjustment features allowing for the vise to be easily rotated, a position and size of an opening of the jaws to be rapidly adjusted, and a clamping force applied with ease.